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Dorsoventral polarity directs cell responses to migration track geometries

How migrating cells differentially adapt and respond to extracellular track geometries remains unknown. Using intravital imaging, we demonstrate that invading cells exhibit dorsoventral (top-to-bottom) polarity in vivo. To investigate the impact of dorsoventral polarity on cell locomotion through di...

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Bibliografski detalji
Izdano u:Sci Adv
Glavni autori: Wisniewski, Emily O., Mistriotis, Panagiotis, Bera, Kaustav, Law, Robert A., Zhang, Jitao, Nikolic, Milos, Weiger, Michael, Parlani, Maria, Tuntithavornwat, Soontorn, Afthinos, Alexandros, Zhao, Runchen, Wirtz, Denis, Kalab, Petr, Scarcelli, Giuliano, Friedl, Peter, Konstantopoulos, Konstantinos
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399493/
https://ncbi.nlm.nih.gov/pubmed/32789173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba6505
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