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A Direct Podocalyxin-Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells

The sialoglycoprotein podocalyxin is absent in normal pancreas but is overexpressed in pancreatic cancer and is associated with poor clinical outcome. Here we investigate the role of podocalyxin in migration and metastasis of pancreatic adenocarcinomas using SW1990 and Pa03c as cell models. Although...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wong, Bin Sheng, Shea, Daniel J., Mistriotis, Panagiotis, Tuntithavornwat, Soontorn, Law, Robert A., Bieber, Jake M., Zheng, Lei, Konstantopoulos, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548656/
https://ncbi.nlm.nih.gov/pubmed/30975647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3369
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