A Direct Podocalyxin-Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells

The sialoglycoprotein podocalyxin is absent in normal pancreas but is overexpressed in pancreatic cancer and is associated with poor clinical outcome. Here we investigate the role of podocalyxin in migration and metastasis of pancreatic adenocarcinomas using SW1990 and Pa03c as cell models. Although...

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Vydáno v:Cancer Res
Hlavní autoři: Wong, Bin Sheng, Shea, Daniel J., Mistriotis, Panagiotis, Tuntithavornwat, Soontorn, Law, Robert A., Bieber, Jake M., Zheng, Lei, Konstantopoulos, Konstantinos
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548656/
https://ncbi.nlm.nih.gov/pubmed/30975647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3369
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