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Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53

Eukaryotic replication origins are licensed by the loading of the replicative DNA helicase, Mcm2-7, in inactive double hexameric form around DNA. Subsequent origin activation is under control of multiple protein kinases that either promote or inhibit origin activation, which is important for genome...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Abd Wahab, Syafiq, Remus, Dirk
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398698/
https://ncbi.nlm.nih.gov/pubmed/32701054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58571
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