Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

CD8(+) tissue-resident memory T cells (T(RM) cells) are poised at the portals of infection and provide long-term protective immunity. Despite their critical roles, the precise mechanics governing T(RM) cell reactivation in situ are unknown. Using a TCR-transgenic Nur77-GFP reporter to distinguish “a...

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Publicado en:J Exp Med
Main Authors: Low, Jun Siong, Farsakoglu, Yagmur, Amezcua Vesely, Maria Carolina, Sefik, Esen, Kelly, Joseph B., Harman, Christian C.D., Jackson, Ruaidhri, Shyer, Justin A., Jiang, Xiaodong, Cauley, Linda S., Flavell, Richard A., Kaech, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398161/
https://ncbi.nlm.nih.gov/pubmed/32525985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192291
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