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Motility Matters: How CD8(+) T-Cell Trafficking Influences Effector and Memory Cell Differentiation

Immunological memory is a hallmark of adaptive immunity that confers long-lasting protection from reinfections. Memory CD8(+) T cells provide protection by actively scanning for their cognate antigen and migrating into inflamed tissues. Trafficking patterns of CD8(+) T cells are also a major determi...

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Veröffentlicht in:Cold Spring Harb Perspect Biol
Hauptverfasser: Farsakoglu, Yagmur, McDonald, Bryan, Kaech, Susan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327832/
https://ncbi.nlm.nih.gov/pubmed/34001529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a038075
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