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Smad4 Promotes Differentiation of Effector and Circulating Memory CD8 T Cells but Is Dispensable for Tissue-Resident Memory CD8 T Cells

Tissue-resident memory CD8 T cells are a unique subset of virus-specific CTLs that bolster local immune responses after becoming lodged in previously infected tissues. These cells provide enhanced protection by intercepting returning pathogens before a new infection gets established. In contrast, ce...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hu, Yinghong, Lee, Young-Tae, Kaech, Susan M., Garvy, Beth, Cauley, Linda S.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337487/
https://ncbi.nlm.nih.gov/pubmed/25637015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402369
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