Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

CD8(+) tissue-resident memory T cells (T(RM) cells) are poised at the portals of infection and provide long-term protective immunity. Despite their critical roles, the precise mechanics governing T(RM) cell reactivation in situ are unknown. Using a TCR-transgenic Nur77-GFP reporter to distinguish “a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Low, Jun Siong, Farsakoglu, Yagmur, Amezcua Vesely, Maria Carolina, Sefik, Esen, Kelly, Joseph B., Harman, Christian C.D., Jackson, Ruaidhri, Shyer, Justin A., Jiang, Xiaodong, Cauley, Linda S., Flavell, Richard A., Kaech, Susan M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398161/
https://ncbi.nlm.nih.gov/pubmed/32525985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192291
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