Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

CD8(+) tissue-resident memory T cells (T(RM) cells) are poised at the portals of infection and provide long-term protective immunity. Despite their critical roles, the precise mechanics governing T(RM) cell reactivation in situ are unknown. Using a TCR-transgenic Nur77-GFP reporter to distinguish “a...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Low, Jun Siong, Farsakoglu, Yagmur, Amezcua Vesely, Maria Carolina, Sefik, Esen, Kelly, Joseph B., Harman, Christian C.D., Jackson, Ruaidhri, Shyer, Justin A., Jiang, Xiaodong, Cauley, Linda S., Flavell, Richard A., Kaech, Susan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398161/
https://ncbi.nlm.nih.gov/pubmed/32525985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192291
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