TFAP2E Methylation and Expression Status Does Not Predict Response to 5FU-based Chemotherapy in Colorectal Cancer

PURPOSE: A recent study reported that 5-fluorouracil (5FU)-based chemotherapy is less effective in treating advanced colorectal cancer (CRC) patients demonstrating hypermethylation of TFAP2E gene. The aim of our study was to confirm and validate these findings in large, uniformly treated, well-chara...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Murcia, Oscar, Jover, Rodrigo, Egoavil, Cecilia, Perez-Carbonell, Lucia, Juárez, Miriam, Hernández-Illán, Eva, Rojas, Estefania, Alenda, Cristina, Balaguer, Francesc, Andreu, Montserrat, Llor, Xavier, Castells, Antoni, Boland, C. Richard, Goel, Ajay
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396148/
https://ncbi.nlm.nih.gov/pubmed/29535127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2940
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