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Detection of BRAF V600E Mutation in Colorectal Cancer : Comparison of Automatic Sequencing and Real-Time Chemistry Methodology
Mutation V600E of BRAF, a kinase-encoding gene from the RAS/RAF/MAPK pathway, in colorectal carcinoma (CRC) suggests a sporadic origin of the disease, providing an exclusion criterion for hereditary nonpolyposis colorectal cancer. Here we describe detection of this mutation by real-time chemistry Ta...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876165/ https://ncbi.nlm.nih.gov/pubmed/17065421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.060070 |
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