Detection of BRAF V600E Mutation in Colorectal Cancer : Comparison of Automatic Sequencing and Real-Time Chemistry Methodology

Mutation V600E of BRAF, a kinase-encoding gene from the RAS/RAF/MAPK pathway, in colorectal carcinoma (CRC) suggests a sporadic origin of the disease, providing an exclusion criterion for hereditary nonpolyposis colorectal cancer. Here we describe detection of this mutation by real-time chemistry Ta...

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Detalhes bibliográficos
Main Authors: Benlloch, Susana, Payá, Artemio, Alenda, Cristina, Bessa, Xavier, Andreu, Montserrat, Jover, Rodrigo, Castells, Antoni, Llor, Xavier, Aranda, F. Ignacio, Massutí, Bartomeu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876165/
https://ncbi.nlm.nih.gov/pubmed/17065421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.060070
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