TFAP2E Methylation and Expression Status Does Not Predict Response to 5FU-based Chemotherapy in Colorectal Cancer

PURPOSE: A recent study reported that 5-fluorouracil (5FU)-based chemotherapy is less effective in treating advanced colorectal cancer (CRC) patients demonstrating hypermethylation of TFAP2E gene. The aim of our study was to confirm and validate these findings in large, uniformly treated, well-chara...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Clin Cancer Res
मुख्य लेखकों: Murcia, Oscar, Jover, Rodrigo, Egoavil, Cecilia, Perez-Carbonell, Lucia, Juárez, Miriam, Hernández-Illán, Eva, Rojas, Estefania, Alenda, Cristina, Balaguer, Francesc, Andreu, Montserrat, Llor, Xavier, Castells, Antoni, Boland, C. Richard, Goel, Ajay
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396148/
https://ncbi.nlm.nih.gov/pubmed/29535127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2940
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