In vivo anticancer activity of a rhodium metalloinsertor in the HCT116 xenograft tumor model

Mismatch repair (MMR) deficiencies are a hallmark of various cancers causing accumulation of DNA mutations and mismatches, which often results in chemotherapy resistance. Metalloinsertor complexes, including [Rh(chrysi)(phen)(PPO)]Cl(2) (Rh-PPO), specifically target DNA mismatches and selectively in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Threatt, Stephanie D., Synold, Timothy W., Wu, Jun, Barton, Jacqueline K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395490/
https://ncbi.nlm.nih.gov/pubmed/32661159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006569117
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker