Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin

Immunotoxins are antibody–toxin fusion proteins under development as cancer therapeutics. In early clinical trials, immunotoxins constructed with domains II and III of Pseudomonas exotoxin (termed PE38), have produced a high rate of complete remissions in Hairy Cell Leukemia and objective responses...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Immunol Immunother
Auteurs principaux: Sarnovsky, Robert, Tendler, Tara, Makowski, Matheusz, Kiley, Maureen, Antignani, Antonella, Traini, Roberta, Zhang, Jingli, Hassan, Raffit, FitzGerald, David J.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2009
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394282/
https://ncbi.nlm.nih.gov/pubmed/20091030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0794-4
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