Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin

Immunotoxins are antibody–toxin fusion proteins under development as cancer therapeutics. In early clinical trials, immunotoxins constructed with domains II and III of Pseudomonas exotoxin (termed PE38), have produced a high rate of complete remissions in Hairy Cell Leukemia and objective responses...

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Veröffentlicht in:Cancer Immunol Immunother
Hauptverfasser: Sarnovsky, Robert, Tendler, Tara, Makowski, Matheusz, Kiley, Maureen, Antignani, Antonella, Traini, Roberta, Zhang, Jingli, Hassan, Raffit, FitzGerald, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394282/
https://ncbi.nlm.nih.gov/pubmed/20091030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0794-4
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