Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin

Immunotoxins are antibody–toxin fusion proteins under development as cancer therapeutics. In early clinical trials, immunotoxins constructed with domains II and III of Pseudomonas exotoxin (termed PE38), have produced a high rate of complete remissions in Hairy Cell Leukemia and objective responses...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Sarnovsky, Robert, Tendler, Tara, Makowski, Matheusz, Kiley, Maureen, Antignani, Antonella, Traini, Roberta, Zhang, Jingli, Hassan, Raffit, FitzGerald, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394282/
https://ncbi.nlm.nih.gov/pubmed/20091030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0794-4
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