Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin

Immunotoxins are antibody–toxin fusion proteins under development as cancer therapeutics. In early clinical trials, immunotoxins constructed with domains II and III of Pseudomonas exotoxin (termed PE38), have produced a high rate of complete remissions in Hairy Cell Leukemia and objective responses...

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Vydáno v:Cancer Immunol Immunother
Hlavní autoři: Sarnovsky, Robert, Tendler, Tara, Makowski, Matheusz, Kiley, Maureen, Antignani, Antonella, Traini, Roberta, Zhang, Jingli, Hassan, Raffit, FitzGerald, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2009
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394282/
https://ncbi.nlm.nih.gov/pubmed/20091030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0794-4
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