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PD-L1 binds to B7-1 only in cis on the same cell surface
Programmed death ligand 1 (PD-L1)–mediated immune suppression regulates peripheral tolerance and is often co-opted by tumors to evade immune attack. PD-L1 binds to PD-1 but also binds to B7–1 (CD80) to regulate T-cell function. The binding interaction of PD-L1 with B7–1 and its functional role need...
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| Publicado no: | Cancer Immunol Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7394266/ https://ncbi.nlm.nih.gov/pubmed/29871885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0316 |
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