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Interaction of Human PD-L1 and B7-1

Numerous studies have pointed to the role of Programmed Death-1 Ligand 1 (PD-L1) in regulating tolerance, chronic infection, and tumor immunity. Recently, we have identified murine B7-1 as a new binding partner for murine PD-L1. Human and mouse B7-1 share only 46% identity, leading us to question wh...

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Detalhes bibliográficos
Main Authors: Butte, Manish J., Pena-Cruz, Victor, Kim, Mi-Jung, Freeman, Gordon J., Sharpe, Arlene H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764616/
https://ncbi.nlm.nih.gov/pubmed/18585785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.05.014
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