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PD-L1 interacts specifically with B7-1 to inhibit T cell proliferation

Pathways in the B7:CD28 family regulate T cell activation and tolerance. B7 dependent responses in CD28/CTLA-4(-/-) T cells together with reports of stimulatory and inhibitory functions for PD-L1 and PD-L2 have suggested additional receptors for these B7 family members. We show that B7-1 and PD-L1 i...

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Detalhes bibliográficos
Main Authors: Butte, Manish J., Keir, Mary E., Phamduy, Theresa B., Freeman, Gordon J., Sharpe, Arlene H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707944/
https://ncbi.nlm.nih.gov/pubmed/17629517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.05.016
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