Microglial microRNAs mediate sex-specific responses to tau pathology

Sex is a key modifier of neurological disease outcomes. Microglia are implicated in neurological diseases and modulated by miRNAs, but it is unknown whether microglial miRNAs have sex-specific influences on disease. We show that microglial miRNA expression differs in males and females and that loss...

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Bibliografiska uppgifter
I publikationen:Nat Neurosci
Huvudupphovsmän: Kodama, Lay, Guzman, Elmer, Etchegaray, Jon I., Li, Yaqiao, Sayed, Faten A., Zhou, Lu, Zhou, Yungui, Zhan, Lihong, Le, David, Udeochu, Joe C., Clelland, Claire D., Cheng, Zuolin, Yu, Guoqiang, Li, Qingyun, Kosik, Kenneth S., Gan, Li
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394069/
https://ncbi.nlm.nih.gov/pubmed/31873194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0560-7
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