A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain

Microglia are the resident myeloid cells in the central nervous system (CNS). The majority of microglia rely on CSF1R signaling for survival. However, a small subset of microglia in mouse brains can survive without CSF1R signaling and reestablish the microglial homeostatic population after CSF1R sig...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhan, Lihong, Fan, Li, Kodama, Lay, Sohn, Peter Dongmin, Wong, Man Ying, Mousa, Gergey Alzaem, Zhou, Yungui, Li, Yaqiao, Gan, Li
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591254/
https://ncbi.nlm.nih.gov/pubmed/33054973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51796
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