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POT1-TPP1 telomere length regulation and disease

Telomeres are DNA repeats at the ends of linear chromosomes and are replicated by telomerase, a ribonucleoprotein reverse transcriptase. Telomere length regulation and chromosome end capping are essential for genome stability and are mediated primarily by the shelterin and CST complexes. POT1-TPP1,...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Aramburu, Tomas, Plucinsky, Sarah, Skordalakes, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385035/
https://ncbi.nlm.nih.gov/pubmed/32774788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.06.040
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