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POT1 Association with TRF2 Regulates Telomere Length

Deleting the OB folds encoding the telomeric single-stranded DNA (ssDNA)-binding activity of the human telomeric protein POT1 induces significant telomere elongation, suggesting that at least one critical aspect of the regulation of telomere length is disrupted by this POT1(ΔOB) mutant protein. POT1...

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Detalles Bibliográficos
Main Authors: Kendellen, Megan F., Barrientos, Katharine S., Counter, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756888/
https://ncbi.nlm.nih.gov/pubmed/19651898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00286-09
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