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POT1 and TRF2 Cooperate To Maintain Telomeric Integrity

Mammalian telomeric DNA contains duplex TTAGGG repeats and single-stranded overhangs. POT1 (protection of telomeres 1) is a telomere-specific single-stranded DNA-binding protein, highly conserved in eukaryotes. The biological function of human POT1 is not well understood. In the present study, we de...

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Hlavní autoři: Yang, Qin, Zheng, Yun-Ling, Harris, Curtis C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC544002/
https://ncbi.nlm.nih.gov/pubmed/15657433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.3.1070-1080.2005
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