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POT1 Association with TRF2 Regulates Telomere Length
Deleting the OB folds encoding the telomeric single-stranded DNA (ssDNA)-binding activity of the human telomeric protein POT1 induces significant telomere elongation, suggesting that at least one critical aspect of the regulation of telomere length is disrupted by this POT1(ΔOB) mutant protein. POT1...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756888/ https://ncbi.nlm.nih.gov/pubmed/19651898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00286-09 |
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