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Constitutive activity of a G protein‐coupled receptor, DRD1, contributes to human cerebral organoid formation
The intricate balance of neural stem cell (NSC) amplification and neurogenesis is central to nervous system development. Dopamine D1 receptor (DRD1) is a typical G protein‐coupled receptor (GPCR) mainly expressed in neurogenic area, with high constitutive activity. The receptor appears in the embryo...
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| Опубликовано в: : | Stem Cells |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley & Sons, Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384186/ https://ncbi.nlm.nih.gov/pubmed/32052915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3156 |
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