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Constitutive G protein coupling profiles of understudied orphan GPCRs
A large number of GPCRs are potentially valuable drug targets but remain understudied. Many of these lack well-validated activating ligands and are considered “orphan” receptors, and G protein coupling profiles have not been defined for many orphan GPCRs. Here we asked if constitutive receptor activ...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8062009/ https://ncbi.nlm.nih.gov/pubmed/33886554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247743 |
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