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Constitutive phospholipid scramblase activity of a G Protein-coupled receptor*

Opsin, the rhodopsin apoprotein, was recently shown to be an ATP-independent flippase (or scramblase) that equilibrates phospholipids across photoreceptor disc membranes in mammalian retina, a process required for disc homeostasis. Here we show that scrambling is a constitutive activity of rhodopsin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Goren, Michael A., Morizumi, Takefumi, Menon, Indu, Joseph, Jeremiah S., Dittman, Jeremy S., Cherezov, Vadim, Stevens, Raymond C., Ernst, Oliver P., Menon, Anant K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198942/
https://ncbi.nlm.nih.gov/pubmed/25296113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6115
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