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Discovery and Validation of Novel Peptide Agonists for G-protein-coupled Receptors
G-protein-coupled receptors (GPCRs) represent an important group of targets for pharmaceutical therapeutics. The completion of the human genome revealed a large number of putative GPCRs. However, the identification of their natural ligands, and especially peptides, suffers from low discovery rates,...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259865/ https://ncbi.nlm.nih.gov/pubmed/18854305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805181200 |
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