Discovery and Validation of Novel Peptide Agonists for G-protein-coupled Receptors

G-protein-coupled receptors (GPCRs) represent an important group of targets for pharmaceutical therapeutics. The completion of the human genome revealed a large number of putative GPCRs. However, the identification of their natural ligands, and especially peptides, suffers from low discovery rates,...

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Bibliographische Detailangaben
Hauptverfasser: Shemesh, Ronen, Toporik, Amir, Levine, Zurit, Hecht, Iris, Rotman, Galit, Wool, Assaf, Dahary, Dvir, Gofer, Eyal, Kliger, Yossef, Soffer, Michal Ayalon, Rosenberg, Avi, Eshel, Dani, Cohen, Yossi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Genomics, Proteomics, and Bioinformatics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259865/
https://ncbi.nlm.nih.gov/pubmed/18854305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805181200
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