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Constitutive Activity of Serotonin Receptor 6 Regulates Human Cerebral Organoids Formation and Depression-like Behaviors
Serotonin receptor 6 (5-HT(6)R), a typical G protein-coupled receptor (GPCR) mainly expressed in the neurogenic area with constitutive activity, is of particular interest as a promising target for emotional impairment. Here, we found that 5-HT(6)R was highly expressed in human NSCs and activation of...
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| 發表在: | Stem Cell Reports |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7815944/ https://ncbi.nlm.nih.gov/pubmed/33357407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.11.015 |
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