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Genetically engineered cerebral organoids model brain tumour formation

Brain tumours are among the most lethal and devastating cancers. Their study is limited by genetic heterogeneity and the incompleteness of available laboratory models. Three-dimensional organoid culture models offer innovative possibilities for modelling human disease. Here, we establish a 3D in vit...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Bian, Shan, Repic, Marko, Guo, Zhenming, Kavirayani, Anoop, Burkard, Thomas, Bagley, Joshua A., Krauditsch, Christian, Knoblich, Jürgen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071863/
https://ncbi.nlm.nih.gov/pubmed/30038414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0070-7
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