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Genetically engineered cerebral organoids model brain tumour formation

Brain tumours are among the most lethal and devastating cancers. Their study is limited by genetic heterogeneity and the incompleteness of available laboratory models. Three-dimensional organoid culture models offer innovative possibilities for modelling human disease. Here, we establish a 3D in vit...

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Détails bibliographiques
Publié dans:Nat Methods
Auteurs principaux: Bian, Shan, Repic, Marko, Guo, Zhenming, Kavirayani, Anoop, Burkard, Thomas, Bagley, Joshua A., Krauditsch, Christian, Knoblich, Jürgen A.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071863/
https://ncbi.nlm.nih.gov/pubmed/30038414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0070-7
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