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Guided self-organization and cortical plate formation in human brain organoids

Three-dimensional cell culture models have either relied on the self-organizing properties of mammalian cells1–6 or used bioengineered constructs to arrange cells in an organ-like configuration7,8. While self-organizing organoids excel at recapitulating early developmental events, bioengineered cons...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Lancaster, Madeline A., Corsini, Nina S., Wolfinger, Simone, Gustafson, E. Hilary, Phillips, Alex, Burkard, Thomas R., Otani, Tomoki, Livesey, Frederick J., Knoblich, Juergen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824977/
https://ncbi.nlm.nih.gov/pubmed/28562594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3906
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