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Genetically engineered cerebral organoids model brain tumor formation

Brain tumors are among the most lethal and devastating cancers. Their study is limited by genetic heterogeneity and the incompleteness of available laboratory models. Three-dimensional organoid culture models offer innovative possibilities for the modeling of human disease. Here we establish a 3D in...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Bian, Shan, Repic, Marko, Guo, Zhenming, Kavirayani, Anoop, Burkard, Thomas, Bagley, Joshua A., Krauditsch, Christian, Knoblich, Jürgen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345371/
https://ncbi.nlm.nih.gov/pubmed/30135560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0118-8
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