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Assessment of biased agonism at the A(3) adenosine receptor using β-arrestin and miniGα(i) recruitment assays

The A(3) adenosine receptor (A(3)AR) is a G protein-coupled receptor that is involved in a wide variety of physiological and pathological processes, such as cancer. However, the use of compounds pharmacologically targeting this receptor remains limited in clinical practice, despite extensive efforts...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem Pharmacol
Prif Awduron: Pottie, Eline, Tosh, Dilip K., Gao, Zhan-Guo, Jacobson, Kenneth A., Stove, Christophe P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382964/
https://ncbi.nlm.nih.gov/pubmed/32224136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.113934
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