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Probing Structure-Activity Relationship in β-Arrestin2 Recruitment of Diversely Substituted Adenosine Derivatives
In the adenosine receptor (AR) subfamily of G protein-coupled receptors (GPCRs), biased agonism has been described for the human A(1)AR, A(2B)AR and A(3)AR. While diverse A(3)AR agonists have been evaluated for receptor binding and Gi-mediated cAMP signalling, the β-arrestin2 (βarr2) pathway has bee...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6530469/ https://ncbi.nlm.nih.gov/pubmed/30292756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.10.003 |
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