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Structure–Activity Relationships and Molecular Modeling of 1,2,4-Triazoles as Adenosine Receptor Antagonists
[Image: see text] The structure–activity relationship (SAR) for a novel class of 1,2,4-triazole antagonists of the human A(2A) adenosine receptor (hA(2A)AR) was explored. Thirty-three analogs of a ligand that was discovered in a structure-based virtual screen against the hA(2A)AR were tested in hA(1...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American
Chemical Society
2012
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549271/ https://ncbi.nlm.nih.gov/pubmed/23342198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300097g |
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