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Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis

The scavenger receptor CD163 is highly expressed in macrophages in sites of chronic inflammation where it has a not yet defined role. Here we have investigated development of collagen-induced arthritis (CIA) and collagen antibody-induced arthritis (CAIA) in CD163-deficient C57BL/6 mice. Compared to...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Svendsen, Pia, Etzerodt, Anders, Deleuran, Bent W., Moestrup, Søren K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382459/
https://ncbi.nlm.nih.gov/pubmed/32710083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69018-7
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