Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of ‘soluble CD163’ in plasma

CD163 is the macrophage receptor for uptake of hemoglobin-haptoglobin complexes. The human receptor can be shed from the macrophage surface owing to a cleavage site for the inflammation-inducible TACE/ADAM17 enzyme. Accordingly, plasma ‘soluble CD163’ (sCD163) has become a biomarker for macrophage a...

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Publicado en:Sci Rep
Main Authors: Etzerodt, Anders, Berg, Ronan M. G., Plovsing, Ronni R., Andersen, Morten N., Bebien, Magali, Habbeddine, Mohamed, Lawrence, Toby, Møller, Holger J., Moestrup, Søren K.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234032/
https://ncbi.nlm.nih.gov/pubmed/28084321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40286
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