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The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging
The haptoglobin- (Hp-) CD163-heme oxygenase-1 (HO-1) pathway is an efficient captor-receptor-enzyme system to circumvent the hemoglobin (Hb)/heme-induced toxicity during physiological and pathological hemolyses. In this pathway, Hb tightly binds to Hp leading to CD163-mediated uptake of the complex...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678498/ https://ncbi.nlm.nih.gov/pubmed/23781295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/523652 |
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