Targeting the Hemoglobin Scavenger receptor CD163 in Macrophages Highly Increases the Anti-inflammatory Potency of Dexamethasone

Synthetic glucocorticoids are potent anti-inflammatory drugs but serious side effects such as bone mobilization, muscle mass loss, immunosuppression, and metabolic alterations make glucocorticoid therapy a difficult balance. The therapeutic anti-inflammatory effect of glucocorticoids relies largely...

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Detalhes bibliográficos
Main Authors: Graversen, Jonas H, Svendsen, Pia, Dagnæs-Hansen, Frederik, Dal, Jakob, Anton, Gabriele, Etzerodt, Anders, Petersen, Mikkel D, Christensen, Peter A, Møller, Holger J, Moestrup, Søren K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412497/
https://ncbi.nlm.nih.gov/pubmed/22643864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.103
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