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A mechanistic view of enzyme evolution
New enzyme functions often evolve through the recruitment and optimization of latent promiscuous activities. How do mutations alter the molecular architecture of enzymes to enhance their activities? Can we infer general mechanisms that are common to most enzymes, or does each enzyme require a unique...
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| Publicado no: | Protein Sci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380680/ https://ncbi.nlm.nih.gov/pubmed/32557882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3901 |
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