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A mechanistic view of enzyme evolution
New enzyme functions often evolve through the recruitment and optimization of latent promiscuous activities. How do mutations alter the molecular architecture of enzymes to enhance their activities? Can we infer general mechanisms that are common to most enzymes, or does each enzyme require a unique...
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| Publicat a: | Protein Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Inc.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380680/ https://ncbi.nlm.nih.gov/pubmed/32557882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3901 |
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