Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma

INTRODUCTION: Surgical resection and systemic chemotherapy with temozolomide remain the mainstay for treatment of glioblastoma. However, many patients are not candidates for surgical resection given inaccessible tumor location or poor health status. Furthermore, despite being first line treatment, t...

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Publicado en:PLoS One
Main Authors: Garrett, Matthew C., O’Shea, Timothy M., Wollenberg, Alexander L., Bernstein, Alexander M., Hung, Derek, Staarman, Brittany, Soto, Horacio, Deming, Timothy J., Sofroniew, Michael V., Kornblum, Harley I.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380637/
https://ncbi.nlm.nih.gov/pubmed/32706829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219632
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