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Tunable diblock copolypeptide hydrogel depots for local delivery of hydrophobic molecules in healthy and injured central nervous system

Many hydrophobic small molecules are available to regulate gene expression and other cellular functions. Locally restricted application of such molecules in the central nervous system (CNS) would be desirable in many experimental and therapeutic settings, but is limited by a lack of innocuous vehicl...

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Detalhes bibliográficos
Main Authors: Zhang, Shanshan, Anderson, Mark A., Ao, Yan, Khakh, Baljit S., Fan, Jessica, Deming, Timothy J., Sofroniew, Michael V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984939/
https://ncbi.nlm.nih.gov/pubmed/24314556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.11.005
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