Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma

INTRODUCTION: Surgical resection and systemic chemotherapy with temozolomide remain the mainstay for treatment of glioblastoma. However, many patients are not candidates for surgical resection given inaccessible tumor location or poor health status. Furthermore, despite being first line treatment, t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garrett, Matthew C., O’Shea, Timothy M., Wollenberg, Alexander L., Bernstein, Alexander M., Hung, Derek, Staarman, Brittany, Soto, Horacio, Deming, Timothy J., Sofroniew, Michael V., Kornblum, Harley I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380637/
https://ncbi.nlm.nih.gov/pubmed/32706829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219632
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