SCDT-08. INJECTABLE DIBLOCK COPOLYPEPTIDE HYDROGEL PROVIDES A PROLONGED LOCAL DEPOT OF PACLITAXEL THAT PROVIDES LOCAL TUMOR CONTROL IN A PATIENT-DERIVED XENOTRANSPLANT MODEL OF GLIOBLASTOMA

INTRODUCTION: The treatment of glioblastoma is limited by the fact that most oral/IV chemotherapy regimens are not able to cross the blood-brain barrier. While previous studies have designed modalities to directly deliver chemotherapeutic compounds in situ, few if any of these studies directly teste...

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Vydáno v:Neuro Oncol
Hlavní autoři: Garrett, Matthew, O’Shea, Timothy, Bernstein, Alexander, Wollenberg, Alexander, Hung, Derek, Deming, Timothy, Kornblum, Harley, Sofroniew, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692656/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1091
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