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Blending of diblock and triblock copolypeptide amphiphiles yields cell penetrating vesicles with low toxicity

We have prepared dual hydrophilic triblock copolypeptide vesicles that form both micron and nanometer scale vesicles in aqueous media. The incorporation of terminal homoarginine segments into methionine sulfoxide based vesicles was found to significantly enhance their cellular uptake compared to a d...

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Dettagli Bibliografici
Pubblicato in:Macromol Biosci
Autori principali: Rodriguez, April R., Choe, Uh-Joo, Kamei, Daniel T., Deming, Timothy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408078/
https://ncbi.nlm.nih.gov/pubmed/25323924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201400348
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