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Blending of diblock and triblock copolypeptide amphiphiles yields cell penetrating vesicles with low toxicity

We have prepared dual hydrophilic triblock copolypeptide vesicles that form both micron and nanometer scale vesicles in aqueous media. The incorporation of terminal homoarginine segments into methionine sulfoxide based vesicles was found to significantly enhance their cellular uptake compared to a d...

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Detalhes bibliográficos
Publicado no:Macromol Biosci
Main Authors: Rodriguez, April R., Choe, Uh-Joo, Kamei, Daniel T., Deming, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408078/
https://ncbi.nlm.nih.gov/pubmed/25323924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201400348
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