Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma

INTRODUCTION: Surgical resection and systemic chemotherapy with temozolomide remain the mainstay for treatment of glioblastoma. However, many patients are not candidates for surgical resection given inaccessible tumor location or poor health status. Furthermore, despite being first line treatment, t...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Garrett, Matthew C., O’Shea, Timothy M., Wollenberg, Alexander L., Bernstein, Alexander M., Hung, Derek, Staarman, Brittany, Soto, Horacio, Deming, Timothy J., Sofroniew, Michael V., Kornblum, Harley I.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380637/
https://ncbi.nlm.nih.gov/pubmed/32706829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219632
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